Ph and amine test elements and applications to diagnosis of...

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G01N 33/52 (2006.01) G01N 31/22 (2006.01) G01N 33/483 (2006.01) G01N 33/84 (2006.01)

Patent

CA 2263293

Tests for elevated pH and volatile amines in aqueous fluids are disclosed, including tests useful in the diagnosis of bacterial vaginosis and in other biological conditions. By using formulated indicators and indicators held in matrices that are permeable to gas but not to liquid, the tests provide clear and sharp transitions detectable by visual or machine-readable means rather than by subjective judgements such as small gradations in color or olfactory determinations. The tests lend themselves readily to iconic readouts of the test indications and to the inclusion of positive and negative controls.

L'invention concerne des test, capables de détecter un pH élevé et des amines volatiles dans des fluides aqueux, lesquels tests conviennent particulièrement au diagnostic d'infections vaginales bactériennes et d'autres états biologiques. Grâce aux indicateurs selon la formule et aux indicateurs fixés dans des matrices perméables au gaz mais non aux liquides, les tests donnent des transitions claires et nettes, détectables à l'oeil ou lisibles par machine, au lieu de jugements subjectifs reposant sur d'infimes différences de couleurs ou d'odeurs. Ces tests se prêtent volontiers à des affichages iconiques de résultats, et à l'inclusion de témoins positifs et négatifs.

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