A - Human Necessities – 61 – B
Patent
A - Human Necessities
61
B
A61B 5/00 (2006.01) A61B 5/145 (2006.01)
Patent
CA 2513725
The present invention relates to devices and methods for measuring the pH of blood in the vicinity of a vulnerable plaque. A balloon including an opto- electric device may be positioned proximate a vulnerable plaque. The balloon can be inflated to partially occlude blood flow enabling interaction between lipid laden blood and pH-sensitive material either within the balloon or on the wall(s) of the balloon. The selected pH- ~sensitive material is one whose optical properties change as a function of the pH of blood in the vasculature. An opto-electric device may be used for measuring the optical property and/or the change in the optical characteristics of the pH-sensitive compound.
La présente invention concerne des dispositifs et des méthodes de mesure du pH à proximité d'une plaque vulnérable. Un ballonnet doté d'un dispositif opto-électrique peut être amené à proximité d'une telle plaque. Une fois gonflé, le ballonnet oblitère partiellement le flux sanguin entre le sang chargé de lipides et un matériau sensible au pH, ceci soit à l'intérieur, soit sur la ou les parois du ballonnet. Le matériau sensible au pH est tel que ses propriétés optiques changent en fonction du pH du sang dans les vaisseaux. Un dispositif opto-électrique permet de mesurer la propriété optique et/ou le changement des propriétés optiques du matériau sensible au pH.
Dobrava Eric M.
Kokate Jaydeep Y.
Richardson Leonard B.
Smith Scott R.
Boston Scientific Limited
Smart & Biggar
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