A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/51 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2508437
The present invention relates to a novel pH triggered, targeted controlled release system. The controlled delivery system of the present invention is substantially a free-flowing powder formed of solid hydrophobic nano-spheres comprising pharmaceutical active ingredients that are encapsulated in a pH sensitive micro-spheres. The invention also relates to the processes for preparing the compositions and processes for using same. The controlled release system can be used to target and control the release of pharmaceutical active ingredients onto certain regions of the gastrointestinal tract including the stomach and the small intestine. The invention further pertains to pharmaceutical products comprising the controlled release system of the present invention.
La présente invention concerne un nouveau système de libération contrôlée ciblée à déclenchement fonction du pH qui est principalement constitué d'une poudre à écoulement libre composée de nanosphères solides hydrophobes qui comprennent des ingrédients pharmaceutiques encapsulés dans des microsphères sensibles au pH. La présente invention concerne également des procédés pour préparer les compositions et pour les utiliser. Le système de libération contrôlée selon cette invention peut être utilisé pour cibler et contrôler la libération d'ingrédients pharmaceutiques au niveau de certaines régions du tractus gastro-intestinal, notamment l'estomac et l'intestin grêle. En outre, cette invention concerne des produits pharmaceutiques comprenant ledit système de libération contrôlée.
Shefer Adi
Shefer Samuel David
Borden Ladner Gervais Llp
Salvona Ip Llc
Salvona Llc
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