Phage ligand sensor devices and uses thereof

Details Phage ligand sensor devices and uses thereof Phage ligand sensor devices and uses thereof

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2466220

Methods and compositions for identifying and characterizing one or more ligands of a peptide are provided. In particular, the invention provides a phage ligand sensor device (PLSD) comprising a sensor coupled to a binding element of interest. Binding elements of interest comprise phage displaying at least one foreign peptide. The PLSD and assays find particular use in identifying and characterizing ligand-peptide interactions.

L'invention concerne des procédés et des compositions d'identification et de caractérisation d'un ou plusieurs ligand(s) d'un peptide. L'invention concerne plus particulièrement un capteur de ligands de bactériophages (PLSD) comprenant un capteur couplé à un élément de liaison d'intérêt. Lesdits éléments de liaison renferment des bactériophages affichant au moins un peptide étranger. Le PLSD et les essais biologiques trouvent une application spécifique dans l'identification et la caractérisation d'interactions ligand-peptide.

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