Pharmaceutical aerosol composition

Details Pharmaceutical aerosol composition Pharmaceutical aerosol composition

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 31/58 (2006.01) A61K 38/13 (2006.01) A61M 15/00 (2006.01) A61P 11/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2604327

Sterile compositions for administration as aerosols are described. They contain an active agent which is poorly water-soluble, a non-ionic surfactant component and a phospholipid component. The compositions are suitable for oral or nasal inhalation, but also for topical or oromucosal administration. They are particulary useful for the efficient pulmonary administration of poorly soluble corticosteroids and can be aerosolized with common nebulizers.

La présente invention a trait à des compositions stériles pour administration sous forme d'aérosols. Elles contiennent un principe actif qui est très peu hydrosoluble, un constituant tensioactif non ionique et un constituant phospholipidique. Les compositions conviennent à l'inhalation orale ou nasale, mais également pour une administration topique ou oromucosale. Elles sont particulièrement utiles pour une administration pulmonaire efficace de corticostéroïdes et peuvent être formulées sous forme d'aérosol avec des nébuliseurs classiques.

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