Pharmaceutical aerosol compositions

Details Pharmaceutical aerosol compositions Pharmaceutical aerosol compositions

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2542530

Disclosed are metered dose inhalers having a metering valve to deliver a dose containing an aerosol suspension formulation, said aerosol suspension formulation comprising: an effective amount of Mometasone Furoate, Formoterol or a combination thereof; a suspension medium selected from the group consisting of 1,1,1,2,3,3,3,-heptafluoropropane, 1,1,1,2-tetrafluoroethane; and a solvent that is ethanol; wherein said formulation contains less than about 500 ~g of non-volatile residue as measured by ultraviolet spectroscopy.

L'invention concerne des aérosols-doseurs comportant une soupape de dosage destinée à fournir une dose contenant une formulation de suspension aérosol, ladite formulation comprenant : une quantité efficace de furoate de mometasone, de formoterol ou d'une combinaison de ceux-ci ; un milieu de suspension sélectionné entre le 1,1,1,2,3,3,3,-heptafluoropropane et le 1,1,1,2-tétrafluoroéthane ; et un solvant, l'éthanol. Cette formulation contient une quantité inférieure à 500 ?g environ d'un résidu non volatil, mesurée par spectroscopie ultraviolette.

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