Pharmaceutical aerosol formulation

Details Pharmaceutical aerosol formulation Pharmaceutical aerosol formulation

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 9/16 (2006.01) A61K 31/57 (2006.01)

Patent

CA 2328882

The present invention relates to novel pharmaceutical aerosol formulations comprising: (A) a therapeutic agent in the form of particles coated by at least one coating excipient and at least one surfactant, in suspension in (B) a liquefied propellant gas for the administration of therapeutic agents particularly by the pulmonary route and to a process for preparing these formulations. It also relates to novel particles suitable for use in such formulations.

La présente invention concerne des formulations pour aérosols pharmaceutiques comprenant un agent thérapeutique (A) et un gaz propulseur liquéfié (B). L'agent thérapeutique (A) se présente sous forme de particules enrobées d'au moins un excipient d'enrobage et d'au moins un tensioactif. L'agent thérapeutique (A) est en suspension dans le gaz propulseur liquéfié (B) de façon à permettre l'administration par voie pulmonaire des agents thérapeutiques. L'invention concerne également un procédé d'élaboration de ces formulations. L'invention concerne enfin des particules convenant à l'utilisation dans le cas de telles formulations.

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