Pharmaceutical amiodarone composition for parenteral delivery

Details Pharmaceutical amiodarone composition for parenteral delivery Pharmaceutical amiodarone composition for parenteral delivery

A - Human Necessities

61

K

A61K 31/34 (2006.01) A61K 9/08 (2006.01) A61K 31/343 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2222304

A pharmaceutical composition for parenteral delivery including 1.5-8 wt % of an active principle consisting of amiodarone or a pharmaceutically acceptable salt thereof, a physiologically acceptable buffer solution capable of solubilising the active principle and keeping the pH of the composition at 2.4-3.8, and a non-ionic hydrophilic surfactant.

L'invention a pour objet une composition pharmaceutique pour administration parentérale, caractérisée en ce qu'elle comprend: de 1,5 à 8 % en poids d'un principe actif constitué par l'amiodarone ou un de ses sels pharmaceutiquement acceptables; une solution tampon physiologiquement acceptable capable de solubiliser le principe actif et de maintenir le pH de la composition entre 2,4 et 3,8; un agent tensioactif hydrophile non ionique.

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