Pharmaceutical and nutraceutical products comprising vitamin k2

A - Human Necessities – 61 – K

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A61K 31/122 (2006.01) A61K 31/231 (2006.01) A61K 31/232 (2006.01) A61K 35/60 (2006.01) A61P 9/00 (2006.01) A61P 19/00 (2006.01)

Patent

CA 2657748

A pharmaceutical and nutraceutical product is provided comprising vitamin K2 or a compound within the vitamin K2 class of compounds, optionally and preferably in combination with one or more polyunsaturated fatty acids, either in purified form or as a marine oil (i.e. fish and/or krill oil). Also provided is the use of vitamin K2 or a compound within the vitamin K2 class of compounds, preferably in combination with one or more polyunsaturated fatty acids, either in purified form or as a marine oil, in the treatment or prophylaxis of disorders related to bone, cartilage and the cardiovascular system. Preferred compounds within the vitamin K2 class of compounds are MK-7, MK-8, MK-9 and MK-10, in particular MK-7 or MK-9. The marine oil is preferably krill oil or fish oil.

L'invention concerne un produit pharmaceutique et nutriceutique comprenant de la vitamine K2 ou un composé de la classe des composés de la vitamine K2, éventuellement et de préférence en association avec un ou plusieurs acides gras polyinsaturés, soit sous forme purifiée, soit sous forme d'huile marine (c'est-à-dire huile de poisson et/ou de krill). L'invention fournit également l'utilisation de la vitamine K2 ou d'un composé de la classe des composés de la vitamine K2, de préférence en association avec un ou plusieurs acides gras polyinsaturés, soit sous forme purifiée, soit sous forme d'huile marine, pour le traitement ou la prophylaxie de troubles associés aux os, au cartilage et au système cardiovasculaire. Les composés préférés parmi la classe des composés de la vitamine K2 sont les composés MK-7, MK-8, MK-9 et MK-10, en particulier le composé MK-7 ou le composé MK-9. L'huile marine est de préférence une huile de krill ou une huile de poisson. Fig. 1 Duration of expt (months) Durée de l'expérience (mois) Percentage of reference (%) Pourcentage en référence (%)

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