A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/279
A61K 31/13 (2006.01)
Patent
CA 1056730
ABSTRACT OF TEE DISCLOSURE: Pharmaceutical or veterinary composition for use in the treatment of Parkinson's disease and the correction of extra-pyramidal disturbances provoked by neuroleptics. The composition of the invention comprises as an essential active ingredient at least one methylamine derivative having the general formula: Image (I') wherein R represents methyl, ethyl or n-propyl and R1 and R2 which are the same or different each represents: (a) a straight- or branched-chain alkyl, alkenyl or alkynyl radical having from 1 to 7 carbon atoms when R represents methyl; (b) ethyl, 2-methyl- pentyl or a straiqht- or branched-chain alkenyl or alkynyl radical having from 2 to 7 carbon atoms when R represents ethyl: (c) n-propyl, 2-methyl-butyl, n-pentyl or a straight- or branched- chain alkenyl or alkynyl radical having from 2 to 7 carbon atoms when R represents n-propyl; R1, R2 and R3 being such that no compound of formula (I') possesses more than 13 carbon atoms, or a pharmaceutically acceptable acid addition salt of said methylamine derivative other than 1,1-di-n-propyl-n-butylamine acid fumarate, in association with a pharmaceutical carrier or excipient therefor.
310149
Eymard Pierre
Pigerol Charles
Vernieres Jean-Claude
Werbenec Jean-Pierre
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