A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/496 (2006.01) A61K 31/519 (2006.01) A61P 1/16 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 11/06 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 25/02 (2006.01) A61P 27/02 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2726644
The present invention relates to a pharmaceutical combination which may be useful for the treatment of diseases which involve cell proliferation, which involve migration or apoptosis of myeloma cells, which involve angiogenesis or which involve fibrosis. The invention also relates to a method for the treatment of said diseases, comprising simultaneous, separate or sequential administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
La présente invention concerne une association médicamenteuse qui peut s'avérer utile pour le traitement de maladies donnant lieu à prolifération cellulaire, à migration ou apoptose des cellules myélomateuses, à angiogenèse ou à fibrose. L'invention concerne également un procédé destiné au traitement de ces maladies et consistant en une administration simultanée, séparée, ou séquentielle, de quantités suffisantes de principes actifs spécifiques et/ou un co-traitement avec radiothérapie, dans des proportions engendrant un effet cumulatif et synergique. L'invention concerne enfin l'utilisation de ces composés spécifiques et/ou de la radiothérapie pour la fabrication des préparations des associations médicamenteuses considérées.
Hilberg Frank
Kaiser Rolf
Shapiro David
Stefanic Martin Friedrich
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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