Pharmaceutical combination

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4025 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2627588

This invention relates to a combination product or medicament comprising at least one novel substituted pyrrole derivative and one or more dyslipidemic agents, antiobesity agents, antihyperglycaemic agents, anti-inflammatory agents or mixture thereof. Also provided herein are the pharmaceutical compositions comprising at least one novel substituted pyrrole derivative and one or more dyslipidemic agents, antiobesity agents, antihyperglycaemic agents, anti-inflammatory agents or mixture thereof and optionally together with at least one pharmaceutically acceptable carrier, and methods for the treatment or prophylaxis of cardiovascular diseases, Alzheimer's disease, obesity, diabetes or inflammatory diseases comprising administering to a mammal in need thereof therapeutically effective amounts of combination pharmaceutical composition comprising at least one novel substituted pyrrole derivative and one or more dyslipidemic agents, antiobesity agents, antihyperglycaemic agents, anti-inflammatory agents or mixtures thereof.

La présente invention concerne un produit de combinaison ou un médicament comprenant au moins un dérivé atypique de pyrrole substitué et au moins un agent dyslipidémique, des agents antiobésité, des agents antihyperglycémiques, des agents anti-inflammatoires ou un mélange de ces agents. Sont également fournis des compositions pharmaceutiques comprenant au moins un dérivé substitué de pyrrole et au moins un agent dyslipidémique, des agents antiobésité, antihyperglycémiques, anti-inflammatoires ou un mélange et optionnellement ensemble avec au moins un support pharmaceutiquement acceptable et des procédés de traitement ou la prophylaxie de maladies cardiovasculaires, la maladie d~Alzheimer, l~obésité, le diabète ou les maladies inflammatoires comprenant l~administration à un mammifère qui en a besoin de quantités thérapeutiquement effectives d~une combinaison de composition pharmaceutique comprenant au moins un dérivé de pyrrole substitué atypique et au moins un agent dyslipidémique, des agents antiobésité, antihyperglycémiques, anti-inflammatoires ou des mélanges de ces agents.

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