Pharmaceutical combination composition and associated method

Details Pharmaceutical combination composition and associated method Pharmaceutical combination composition and associated method

A - Human Necessities

61

K

167/164, 167/213

A61K 31/54 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1220423

/EP? TELECOPIER 495;24- 4-84; 4:13PM 2435630903:# 8 ABSTRACT A novel combination pharmaceutical compostion is described, together with a method for making the same, wherein the pharmaceutically active ingredients are seperately milled and then formed into separate granules, and onlu thereafter blended together to form the combination composition. The method for achieving this novel combination composition is also described. In particular, a novel combination composition of triamterene and hydrochlorothiazide having improved bioavialability and novel effectiveness to prevent or eliminate hypokalemic side effects is also described.

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