Pharmaceutical combination comprising eletriptan and sodium...

Details Pharmaceutical combination comprising eletriptan and sodium... Pharmaceutical combination comprising eletriptan and sodium...

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2521902

The present invention provides a combination of (a) eletriptan, or a pharmaceutically acceptable salt thereof, and (b) sodium bicarbonate. The combination provides a rapid absorption of eletriptan when taken orally. The combination is useful for the treatment or prevention of a disease for which a 5-HT1, agonist is indicated, particularly for the treatment of migraine or for the prevention of migraine recurrence.

L'invention porte sur une combinaison pharmaceutique comprenant de l'élétriptan (a) ou un sel pharmaceutiquement acceptable de celui-ci et du bicarbonate de sodium (b). La combinaison permet une absorption rapide de l'élétriptan lorsqu'elle est administrée par voie orale. Une telle combinaison pharmaceutique est utile dans le traitement ou la prophylaxie des maladies où l'on préconise l'usage d'un agoniste 5-HT¿1, ?en particulier dans le traitement de la migraine ou dans la prophylaxie des récurrences migraineuses.

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