Pharmaceutical combinations of torcetrapib and atorvastatin...

A - Human Necessities – 61 – K

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A61K 31/47 (2006.01) A61K 31/40 (2006.01) A61K 31/4015 (2006.01) A61K 31/4025 (2006.01) A61K 45/06 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2419406

Pharmaceutical combinations of a CETP inhibitor and atorvastatin or hydroxy metabolites thereof or a pharmaceutically acceptable salt thereof, methods of using such combination and kits containing such combinations for the treatment of atherosclerosis, angina, elevated cholesterol and low HDL levels and for the management of cardiac risk.

L'invention concerne des combinaisons pharmaceutiques d'un inhibiteur de la CETP (protéine de transfert du cholestérol estérifié) et d'atorvastatine ou de métabolites d'hydroxy de celle-ci ou un sel acceptable sur le plan pharmaceutique de celles-ci, ainsi que des procédés d'utilisations de telles combinaisons et kits renfermant lesdites combinaisons pour le traitement de l'athérosclérose, de l'angine, d'un taux de cholestérol élevé et d'un taux bas de cholestérol HDL (lipoprotéine à densité élevée) et pour la gestion du risque de crise cardiaque.

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