Pharmaceutical composition

A - Human Necessities – 61 – K

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Details

A61K 9/28 (2006.01) A61K 9/00 (2006.01) A61K 31/198 (2006.01) A61K 38/00 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61K 38/23 (2006.01)

Patent

CA 2626933

The present invention provides oral pharmaceutical compositions that enable the successful delivery of drugs in a pharmaceutically effective amount, particularly poly (amino acids) such as peptides, peptidomimetics and proteins, e.g. hormones to a subject via oral administration to accomplish the desired therapeutic effect. The oral pharmaceutical composition comprising a poly (amino acid) as the active ingredient, e.g. a peptide or protein, shows a rapid disintegration and/or dissolution such that the active ingredient is able to attain a therapeutic effect.

La présente invention concerne des compositions pharmaceutiques orales qui permettent l~administration correcte de médicaments en une quantité pharmaceutiquement efficace, en particulier des poly(acides aminés) tels que des peptides, des peptidomimétiques et des protéines, par exemple des hormones à un sujet par administration orale pour réaliser l'effet thérapeutique souhaité. La composition pharmaceutique orale comprenant un poly(acide aminé) en tant qu'ingrédient actif, par exemple un peptide ou une protéine, présente une désintégration et/ou une dissolution rapide de sorte que l'ingrédient actif soit capable de produire un effet thérapeutique.

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