Pharmaceutical composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 9/24 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2709903

Provided herein is a pharmaceutical composition composing an antagonist, an agonist, a seal coat, and a sequestering polymer, w herein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for dealing pain using such compositions is also demonstrated.

La présente invention concerne une composition pharmaceutique constituée d'un antagoniste, d'un agoniste, d'un enrobage étanche et d'un polymère séquestrant, composition pharmaceutique dans laquelle l'antagoniste, l'agoniste, l'enrobage étanche et au moins un polymère séquestrant sont tous des composants d'une seule unité, et dans laquelle l'enrobage étanche forme une couche séparant physiquement l'antagoniste de l'agoniste. L'invention concerne également des procédés de fabrication de ladite composition pharmaceutique. L'invention concerne, en outre, des procédés de prise en charge de la douleur au moyen desdites compositions.

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