A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/34 (2006.01) A61K 9/20 (2006.01) A61K 31/4245 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2660427
Disclosed is a solid pharmaceutical composition containing a low-melting-point oil/fat-like substance, which is improved in drug eluting property and has excellent stability and dissolution property. Specifically, disclosed is a solid pharmaceutical composition comprising a pharmacologically active ingredient, a low-melting-point oil/fat-like substance and a low-viscosity binder. Also disclosed is a method for improving the elution of a pharmacologically active ingredient from a solid pharmaceutical composition comprising the pharmacologically active ingredient and a low-melting-point oil/fat-like substance, characterized by using a low-viscosity binder.
La présente invention concerne une composition pharmaceutique solide contenant une substance de type huile/corps gras à point de fusion bas, dont la propriété d'élution de médicament est améliorée et qui possède d'excellentes propriétés de stabilité et de dissolution. Cette invention concerne plus spécifiquement une composition pharmaceutique solide comprenant un principe pharmacologiquement actif, une substance de type de huile/corps gras à point de fusion bas et un liant de faible viscosité. Cette invention concerne aussi un procédé permettant d'améliorer l'élution d'un principe pharmacologiquement actif d'une composition pharmaceutique solide comprenant ce principe pharmacologiquement actif et une substance de type huile/corps gras à point de fusion bas, caractérisé par l'utilisation d'un liant à faible viscosité.
Nomura Yukihiro
Nonomura Muneo
Fetherstonhaugh & Co.
Takeda Pharmaceutical Company Limited
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