A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/159, 167/163
A61K 47/30 (2006.01) A61K 9/00 (2006.01) A61K 31/35 (2006.01) A61K 31/365 (2006.01)
Patent
CA 2015657
Abstract Pharmaceutical composition A pharmaceutical solution comprising 0.1 to 6.0% w/w sodium cromoglycate, 0.1 to 2.0% w/w carbomer, and sufficient quantity of an inorganic base to confer on the solution a pH of from 5.0 to 6.8, the solution containing no amino acids possesses advantageous properties, particularly for ophthalmic use. The solution preferably contains less than 1.5%, more preferably less than 1.0%, and more than 0.6%, eg about 0.8% w/w carbomer. The solution preferably contains more than 1.0%, eg 2% w/w, and more preferably more than 3%, eg 4% w/w, of sodium cromoglycate. The concentration of sodium cromoglycate in the solution is preferably less than 5% w/w. The preferred inorganic base is sodium hydroxide at a concentration of 0.15 to 0.3% w/w. Also described are processes for the preparation of the solution and methods of treatment involving its use.
Hicks Peter G.
Howard John R.
Fisons Pic
Fisons Plc
Hicks Peter G.
Howard John R.
Ridout & Maybee Llp
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