A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2757345
The present invention is related to meth-ods and pharmaceutical compositions for the therapeutic and diagnostic use in the treatment of diseases and disor-ders which are caused by or associated with neurofibril-lary tangles. In particular, the invention relates to pharma-ceutical composition comprising an antigenic peptide, particularly an antigenic phospho-peptide mimicking a major pathological phospho-epitope of protein tau, for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease.
La présente invention concerne des procédés et des compositions pharmaceutiques destinées à une utilisation thérapeutique et diagnostique dans le traitement de maladies et troubles qui sont provoqués par une dégénérescence fibrillaire ou qui lui sont associés. L'invention concerne en particulier une composition pharmaceutique comprenant un peptide antigénique, particulièrement un phosphopeptide antigénique imitant un phospho-épitope pathologique majeur de la protéine tau, destinée à une utilisation thérapeutique et diagnostique dans le traitement de tauopathies comprenant la maladie d'Alzheimer.
Muhs Andreas
Pfeifer Andrea
Pihlgren Maria
Van Leuven Fred
Ac Immune S.a.
Goudreau Gage Dubuc
K.u. Leuven Research & Development
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