A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/24 (2006.01) A61K 31/485 (2006.01) A61P 19/02 (2006.01)
Patent
CA 2709950
Provided herein are pharmaceutical compositions comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions are also demonstrated.
La présente invention concerne des compositions pharmaceutiques comprenant un antagoniste, un agoniste, un vernis et au moins un polymère séquestrant, l'antagoniste, l'agoniste, le vernis et le polymère séquestrant étant tous des composants d'un ensemble unique, et le vernis formant une couche séparant physiquement l'un de l'autre l'antagoniste de l'agoniste. L'invention concerne également des méthodes de fabrication desdites compositions pharmaceutiques. L'invention concerne enfin des méthodes de traitement de la douleur utilisant lesdites compositions.
Boehm Garth
Johnson Frank
Liang Alfred
Matthews Frank
Stauffer Joseph
Alpharma Pharmaceuticals Llc
Ridout & Maybee Llp
LandOfFree
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