A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61K 9/48 (2006.01) A61K 31/519 (2006.01)
Patent
CA 2438401
The invention relates to a pharmaceutical composition having high bioavailability for oral administration of 4-[4-(3-chloro-4-methoxybenzyl- amino)benzo[4,5]thieno[2,3-d]pyrimidin-2-yl]cyclohexanecarboxylic acid and/or 4-[4-(3-chloro-4-hydroxybenzylamino)benzo[4,5]thieno[2,3-d]-pyrimidin-2- yl]cyclohexanecarboxylic acid or pharmaceutically acceptable salts thereof, to a process for the preparation of the pharmaceutical composition, and to the use thereof.
L'invention se rapporte à une composition pharmaceutique ayant une forte biodisponibilité en termes d'administration par voie orale d'un acide 4-[4-(3-chloro-4-méthoxybenzyle-amino)benzo[4,5]thiéno[2,3-d]pyrimidine-2-yl]cyclohexanecarboxylique et/ou d'un acide 4-[4-(3-chloro-4-hydroxybenzylamino)benzo[4,5]thieno[2,3-d]-pyrimidine-2-yl]cyclohexanecarboxylique ou leurs sels pharmaceutiquement acceptables. L'invention porte également sur un procédé de préparation de la composition pharmaceutique et ses applications.
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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