A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/575 (2006.01) A61K 36/076 (2006.01) A61P 11/02 (2006.01) A61P 11/06 (2006.01) A61P 17/00 (2006.01) A61P 19/02 (2006.01) A61P 27/14 (2006.01) A61P 37/02 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2728112
The present invention is related to a novel use of a lanostane having the following formula (I) or a pharmaceutically acceptable salt thereof in treating a disease induced from immune disorder: Image wherein R1 is either H or CH3; R2 is OCOCH3, =0 or OH; R3 is H or OH; R4 is -C(=CH2)-C(CH3)2R a, in which R a is H or OH, or -CH=C(CH3)-R b, in which R b is CH3 or CH2OH; R5 is H or OH; and R6 is CH3 or CH2OH.
La présente invention a pour objet l'utilisation de lanostanes ou de leurs sels pharmaceutiquement acceptables dans la fabrication de médicaments destinés au traitement de maladies provoquées par une perturbation immunitaire, y compris des maladies allergiques telles que la rhinite allergique, la conjonctivite anaphylactique, l'asthme allergique, la dermite atopique, la sursensibilité de l'oeophage, l'eczéma atopique et la polyarthrite rhumatoïde : où, R1 représente H ou CH3; R2 représente OCOCH3, =O ou OH; R3 représente H ou OH; R4 représente -C(=CH2)-C(CH3)2Ra, où Ra représente H ou OH, ou -CH=C(CH3)-Rb, où Rb représente CH3 ou CH2OH; R5 représente H ou OH; et R6 représente CH3 ou CH2OH.
Lin Hang-Ching
Wu Wen-Mein
Oyen Wiggs Green & Mutala Llp
Sinphar Tian-Li Pharmaceutical Co. Ltd. (hangzhou)
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