Pharmaceutical composition and process

A - Human Necessities – 61 – K

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A61K 33/42 (2006.01) A61K 6/00 (2006.01) A61K 9/16 (2006.01) A61K 31/35 (2006.01) A61L 27/00 (2006.01) A61L 27/36 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2129279

PHARMACEUTICAL COMPOSITION AND PROCESS A b s t r a c t The invention relates to a combination useful for the substitution of bone defects having pathologically developed or being artificially established as well as compositions containing these combinations. The combinations of the invention preferably contain in a weight ratio of 1:9 to 9:1, most preferably 1:1 porous hydroxylapatite and/or tricalcium phosphate in relation to 7-isopropoxyisoflavone, optionally in the form of discrete granules of the active ingredients. The composition contains 7-isopropoxyisoflavone applied onto the surface of porous hydroxylapatite and/or tricalcium phosphate. An advantageous member of the combination according to the invention is 7-isopropoxyisoflavone (generic name: ipriflavone) known as an anti-osteoporotic drug.

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