Pharmaceutical composition and process for its preparation

Details Pharmaceutical composition and process for its preparation Pharmaceutical composition and process for its preparation

A - Human Necessities

61

K

167/182

A61K 31/65 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1334933

A multi-purpose pharmaceutical tablet which can either be readily swallowed or dissolved in water to give a dispersion, comprises a tetracycline, either micro- crystalline cellulose or microfine cellulose, low- substituted hydroxypropylcellulose and a thickening agent, which is preferably hydroxypropyl methylcellulose, and optionally other usual adjuvants. The tablet may be easily swallowed as such, but when immersed in water, it affords a very fine dispersion within 30-60 seconds. The tablet may be prepared by direct compression, or by a wet granulation process in which a granulate is used containing the tetracycline and either microcrystalline cellulose or microfine cellulose, but without a substantial amount of a wet binding substance.

583822

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