Pharmaceutical composition combining tenatoprazole and a...

A - Human Necessities – 61 – K

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A61K 31/444 (2006.01) A61K 31/341 (2006.01) A61K 31/4164 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2503215

The invention relates to a novel pharmaceutical combination. The inventive pharmaceutical composition, which is intended for the treatment of pathologies linked to gastric hyperacidity, comprises a combination of tenatoprazole and one or more histamine H2-receptor antagonists selected from cimetidine, ranitidine, famotidine and nizatidine. The invention is suitable for the treatment of duodenal and gastric ulcers and the symptoms of, and lesions caused by, gastroesophageal reflux.

L'invention concerne une nouvelle association pharmaceutique. La composition pharmaceutique, pour le traitement des pathologies liées à l'hyperacidité gastrique, comporte en combinaison le ténatoprazole et un ou plusieurs antagonistes des récepteurs H2 à l'histamine choisis parmi la cimétidine, la ranitidine, la famotidine et la nizatidine. Application notamment au traitement des ulcères gastriques et duodénaux, et des symptômes et lésions du reflux gastro-oesophagien.

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