Pharmaceutical composition comprising a...

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61P 3/04 (2006.01)

Patent

CA 2604584

Use of a 1- (3-chlorophenyl) -3-alkylpiperazine of formula (I), in racemic (R, S) form or in the form of the (S) enantiomer, in which R is a linear or branched alkyl group having from 1 to 3 carbon atoms, or of an addition salt thereof with a pharmaceutically acceptable organic or inorganic acid, for treating apetite disorder. A pharmaceutical composition that comprises a therapeutically effective amount of a 1-(3-chlorophenyl)-3-alkylpiperazine of formula (I) as previously defined or of an addition salt thereof with a pharmaceutically acceptable organic or inorganic acid, and at least one pharmaceutically acceptable excipient.

L'invention concerne l'utilisation d'une 1-(3-chlorophényl)-3-alkylpipérazine de formule (I), sous forme racémique (R, S) ou sous forme d'énantiomère (S), R représentant un groupe alkyle linéaire ou ramifié qui comprend entre 1 et 3 atomes de carbone, ou d'un sel d'addition de celle-ci comprenant un acide organique ou inorganique acceptable sur le plan pharmaceutique, pour le traitement des troubles de l'alimentation. L'invention concerne également une composition pharmaceutique qui comprend une dose efficace sur le plan thérapeutique d'une 1-(3-chlorophényl)-3-alkylpipérazine de formule (I) telle que définie précédemment ou un sel d'addition de celle-ci comprenant un acide organique ou inorganique acceptable sur le plan pharmaceutique, et au moins un excipient acceptable sur le plan pharmaceutique.

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