Pharmaceutical composition comprising a macrolide...

A - Human Necessities – 61 – K

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A61K 31/436 (2006.01) A61K 31/164 (2006.01) A61P 17/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2519958

Synergistic combination of a macrolide T -cell immunomodulator or immunosuppressant such as 33-epichloro-33desoxyascomycin and a ceramide such as ceramide 3, LPC-9S or linoleic acid are provided, which are useful in particular in the treatment of dermatological or mucosal diseases such as atopic or contact dermatitis or dry skin, asteatotic eczema or xerosis.

L'invention concerne des complexes médicamenteux contenant un immunomodulateur ou immunosuppresseur des lymphocytes T macrolides tel que le 33-épichloro-désoxyascomycine, et un céramide tel que le céramide 3,PC-9S ou de l'acide linoléique, utilisés en particulier dans le traitement des maladies dermatologiques ou des muqueuses, par exemple la dermatite atopique ou de contact, la peau sèche, l'eczéma astéatotique ou le xérosis.

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