A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 36/29 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2612408
Pharmaceutical compositions for the treatment of skin disorders such as psoriasis, acne and eczema, methods of making the compositions and methods of use thereof are described herein. The composition comprises psorberine, an alcohol-water extract isolated from the Mahonia aquifolium plant, and one or more additional active agents. In a preferred embodiment, the one or more active agents is a vitamin D3 analog, such as calcipotriol. The compositions may also contain excipients such as emollients, surfactants, emulsiflers and buffers. The compositions are formulated into a cream, lotion or ointment for topical administration.
L~invention a pour objet des compositions pharmaceutiques pour le traitement de troubles de la peau tels que le psoriasis, l~acné et l~eczéma, des méthodes pour fabriquer les compositions et des méthodes pour les utiliser. La composition comprend de la psorberine, un extrait d'alcool-eau isolé de la plante Mahonia aquifolium, et un ou plusieurs principes actifs supplémentaires. Dans une représentation préférée, lesdits un ou plusieurs principes actifs sont un analogue de la vitamine D3, tel que le calcipotriol. Les compositions peuvent également contenir des excipients tel que des émollients, des tensioactifs, des émulsifiants et des tampons. Les compositions sont formulées en une crème, une lotion ou un onguent pour administration topique.
Gomez Hector J.
Apollo Pharmaceutical Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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