A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/46 (2006.01) A61K 31/13 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2554617
The invention relates to a pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor comprising a 2,3-disubstituted tropane moiety, or a tautomer, a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof (1), and at least one antagonist of N-methyl-D-aspartate (NMDA) receptors or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof (2), and a pharmaceutically acceptable carrier or excipient, and optionally one or more other therapeutic ingredients.
L'invention porte sur une préparation pharmaceutique contenant un inhibiteur de recapture du neurotransmetteur monoamine consistant: en un fragment de tropane disubstitué en 2,3- ou l'un de ses tautomères, sels pharmacocompatibles, solvates, ou dérivés physiologiquement fonctionnels (1), et en au moins un antagoniste des récepteurs du N-méthyl-D-aspartate (NMDA) ou l'un de ses sels pharmacocompatible, solvates, ou dérivés physiologiquement fonctionnels (2), ainsi qu'un support ou excipient pharmacocompatible, et facultativement un ou plusieurs ingrédients thérapeutiques.
Friedl Thomas
Mierau Joachim
Raschig Andreas
Reess Juergen
Boehringer Ingelheim International Gmbh
Mccarthy Tetrault Llp
Neurosearch A/s
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