Pharmaceutical composition comprising a plurality of...

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61K 9/16 (2006.01) A61K 9/22 (2006.01) A61K 9/32 (2006.01) A61K 31/5377 (2006.01)

Patent

CA 2662542

A modified release pharmaceutical composition for oral administration comprising plural mini-tablets, comprising a therapeutically effective amount of a Factor Xa inhibitor within a matrix of polymer(s). The mini-tablets are suitably encapsulated within a gelatin capsule. A manufacturing process and method of use are also described.

L'invention concerne une composition pharmaceutique à libération modifiée qui s'administre par voie orale. La composition pharmaceutique comprend une pluralité de mini-comprimés contenant une quantité thérapeutiquement efficace d'un inhibiteur du facteur XA dans une matrice de polymère(s). Les mini-comprimés sont encapsulés de manière appropriée dans une capsule de gélatine. L'invention concerne en outre un procédé de fabrication et une méthode d'utilisation.

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