Pharmaceutical composition comprising a salt of mirtazapine

Details Pharmaceutical composition comprising a salt of mirtazapine Pharmaceutical composition comprising a salt of mirtazapine

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2561281

The invention provides for a pharmaceutically suitable non-sublimating and solid salt of an enantiomer of mirtazapine, in particular, a mirtazapine salt selected from the list of the salt of maleic acid, hydrobromic acid and fumaric acid, for use in the manufacture of a pharmaceutical composition comprising a salt of S- or R-mirtazapine.

Cette invention concerne un sel solide et ne sublimant pas, pharmaceutiquement acceptable, d'un énantiomère de mirtazapine, en particulier un sel de mirtazapine choisi dans la liste des sels d'acide maléique, d'acide bromhydrique et d'acide fumarique, en vue de son utilisation dans la fabrication d'une composition pharmaceutique comprenant un sel de S-mirtazapine ou de R-mirtazapine.

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