A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/436 (2006.01) A61K 31/4745 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2448248
To provide a pharmaceutical composition comprising a tricyclic compound (I) or its pharmaceutically acceptable salt; monohydric alcohol fatty acid esters; dibasic acid diesters; lower alkylene carbonates; butylene glycol; diethylene glycol mono (lower) alkyl ethers; and thickeners. It is satisfactory in stability and absorption kinetics and/or a low irritation potential.
La présente invention concerne une composition pharmaceutique comprenant un composé tricyclique (I) ou son sel pharmaceutiquement acceptable ; des esters d'acides gras d'alcool monohydrique, des diesters de diacides ; des carbonates d'alkylène inférieur ; du butylène glycol ; des éthers de mono alkyle (inférieur) de diéthylène glycol ; et des épaississants. Cette composition est satisfaisante du point de vue de ses caractéristiques de stabilité et de cinétique d'absorption et/ou pour son faible pouvoir irritant.
Sakai Toshiro
Ueda Satoshi
Yoshida Erika
Fujisawa Pharmaceutical Co. Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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