C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/10 (2006.01) A61K 31/49 (2006.01) A61K 31/5377 (2006.01) A61K 45/06 (2006.01) A61P 31/18 (2006.01) A61P 43/00 (2006.01) C07D 211/04 (2006.01) C07D 241/04 (2006.01)
Patent
CA 2441162
Preventives and/or remedies for HIV infection or preventives and/or remedies for AIDS caused by the infection which contain as the active ingredient at least one member selected from among triazaspiro[5.5]undecane derivatives represented by the general formula (I), quaternary ammonium salts thereof, N- oxides thereof and nontoxic salts of the same optionally combined with at least one preventive and/or remedy for HIV infection: (I) wherein each symbol is as defined in the description. The triazaspiro[5.5]undecane derivatives represented by the general formula (I), quaternary ammonium salts thereof, N- oxides thereof and nontoxic salts of the same are useful in preventing and/or treating HIV infection or preventing and/or treating AIDS caused by the infection.
L'invention porte sur des remèdes préventifs ou curatifs des infections par le VIH et du SIDA contenant comme principe actif au moins un élément choisi parmi des dérivés du triazaspiro [5.5] undécane de formule générale (I) (dont les symboles sont définis dans la description), leurs sels quaternaires d'ammonium, leurs N oxydes et leurs sels non toxiques, combinés à au moins un remède préventif ou curatif des infections par le VIH. L'invention porte également les susdits dérivés du triazaspiro [5.5] undécane utiles comme remèdes préventifs ou curatifs des infections par le VIH et du SIDA.
Maeda Kenji
Mitsuya Hiroaki
Shibayama Shiro
Takaoka Yoshikazu
Ono Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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