C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 309/04 (2006.01) A61K 31/135 (2006.01) A61K 31/185 (2006.01) C07C 211/29 (2006.01) C07C 303/00 (2006.01)
Patent
CA 2501321
The present invention relates to a pharmaceutical composition for treating or preventing obesity, comprising novel crystalline sibutramine methanesulfonate hemihydrate of formula (I). The crystalline sibutramine methanesulfonate hemihydrate according to the present invention has a much higher solubility in water, and enhanced stability under a high humidity/temperature condition, as compared with sibutramine hydrochloride monohydrate.
L'invention concerne une composition pharmaceutique de traitement ou de prévention de l'obésité, comprenant un nouvel hémihydrate de méthanesulfonate de sibutramine cristallin de formule (I). Ledit hémihydrate de méthanesulfonate de sibutramine cristallin de l'invention présente une hydrosolubilité supérieure ainsi qu'une stabilité accrue dans des conditions d'humidité/température élevées, par rapport au monohydrate d'hydrochlorure de sibutramine.
Chang Young-Kil
Kim Han-Kyong
Lee Gwan-Sun
Lee Jae-Cheol
Lee Jae-Heon
Cassan Maclean
Hanmi Holdings Co. Ltd.
Hanmi Pharm. Co. Ltd.
LandOfFree
Pharmaceutical composition comprising crystalline... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical composition comprising crystalline..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition comprising crystalline... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1544493