Pharmaceutical composition comprising gamma-butyrobetaine

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31/205 (2006.01) A61K 31/495 (2006.01) A61K 31/4985 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61P 15/00 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2459719

New medical use for gamma-butyrobetaine is disclosed. Also disclosed are pharmaceutical compositions, containing gamma-butyrobetaine or combination thereof with 3-(2,2,2-trimethylhydrazinium)propionate or sildenafil for oral, parenteral, subcutaneous, transdermal, topical, sublingual, intrauretral, intranasal or rectal application, useful for stimulation of sexual activity and potency in mammals. The disclosed compositions, when applied orally for 6 weeks to non-narcotized male rats substantially increase their sexual activity, decreasing the arousal time, increasing the number of copulations and resultativeness of mounting attempts. When applied by intracavernous or intravenous route said pharmaceutical compositions increase intracorporeal pressure and duration of erection, as well as restore stimulation-induced reflectory erection in narcotized animals.

L'invention concerne l'utilisation dans le domaine médical de la gamma-butyrobétaïne. Cette invention a également trait à des compositions pharmaceutiques contenant la gamma-butyrobétaïne ou un mélange correspondant de 3-(2,2,2-triméthylhydrazinium)propionate ou du sildenafil utilisés dans des applications buccales, parentérales, sous-cutanées, transdermiques, topiques, sublinguales, intra-utérines, intranasales ou rectales destinées à stimuler l'activité sexuelle ou la virilité chez des mammifères. Les compositions de ladite invention, lorsqu'elles sont appliquées oralement pendant 6 semaines à des rats non anesthésiés, augmentent leur activité sexuelle, diminuent le temps du réveil, accroissent le nombre de copulations et la réussite des tentatives de copulations. Lorsque ces compositions sont appliquées par voie intracavitaire ou intraveineuse, elles augmentent la pression intracorporelle et la durée de l'érection, et elles rétablissent l'érection réfléchie induite par stimulations chez des animaux anesthésiés.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Pharmaceutical composition comprising gamma-butyrobetaine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical composition comprising gamma-butyrobetaine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition comprising gamma-butyrobetaine will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1990629

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.