Pharmaceutical composition comprising lactobacillus...

Details Pharmaceutical composition comprising lactobacillus... Pharmaceutical composition comprising lactobacillus...

A - Human Necessities

61

K

A61K 35/74 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2220498

The invention refers to a pharmaceutical composition comprising a Lactobacillus plantarum strain having the ability to colonize human intestinal mucosa in vivo, in combination with arginine and a pharmaceutically acceptable carrier. The composition can be used for curative and/or prophylactic treatment of liver injury and failure and associated bacterial translocation in mammals inclusive man.

L'invention concerne une composition pharmaceutique contenant une souche de Lactobacillus plantarum présentant la faculté de coloniser les muqueuses intestinales d'un être humain in vivo, en combinaison avec de l'arginine et un excipient pharmaceutiquement acceptable. Ladite composition peut être utilisée pour un traitement curatif et/ou prophylactique de lésions et insuffisances hépatiques, ainsi que de la translocation bactérienne associée, chez les mammifères y compris chez l'homme.

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