A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/44 (2006.01) A61K 9/16 (2006.01) A61K 31/365 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01)
Patent
CA 2647893
This invention provides a pharmaceutical composition comprising a lipase inhibitor; a lipophilic oil absorbent selected from the group consisting of hydrogenated castor oil, hydrogenated vegetable oil, glyceryl behenate, glyceryl palmitostearate and a mixture thereof; and a pharmaceutically acceptable additive, an oral formulation of a lipase inhibitor prepared there from and a method for preparing said formulation. The formulation of the present invention can minimize side effects such as oily spotting, fatty/oily stool, abdominal distension and flatus, and thus it can be advantageously used for preventing or treating obesity and hyperlipaemia.
L'invention concerne une composition pharmaceutique comprenant un inhibiteur de lipase, un absorbant d'huile lipophile sélectionné dans le groupe constitué d'huile de ricin hydrogénée, d'huile végétale hydrogénée, de glycéryl béhénate, de glycéryl palmitostéarate ou de leur mélange; un additif acceptable sur le plan pharmaceutique, une formulation orale d'inhibiteur de lipase à base de ladite composition et un procédé servant à préparer ladite formulation. Cette dernière peut limiter au minimum des effets secondaires tels que des taches huileuses, des selles grasses/huileuses, la distension abdominale et les flatulences, et, de ce fait, être utilisée avantageusement afin de prévenir ou de traiter l'obésité et l'hyperlipidémie.
Bin Sung Ah
Kim Jung Ju
Lee Jeong A.
Park Jin Woo
Amorepacific Corporation
Cassan Maclean
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