Pharmaceutical composition comprising microparticle oily...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/10 (2006.01) A61K 9/16 (2006.01) A61K 31/506 (2006.01) A61K 45/00 (2006.01) A61K 47/14 (2006.01) A61K 47/44 (2006.01) A61P 1/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2677842

Disclosed is a pharmaceutical composition containing a base-in-water suspension of particles of a pharmaceutically active ingredient component having an average particle diameter of not more than 20 µm. This pharmaceutical composition enables to attain extremely high intestinal absorption and biological availability of the pharmaceutically active ingredient, particularly when the pharmaceutically active ingredient is poorly water-soluble.

L'invention porte sur une composition pharmaceutique contenant une suspension base-dans-l'eau de particules d'un composant d'ingrédient actif du point de vue pharmaceutique ayant un diamètre moyen de particule inférieur ou égal à 20 µm. Cette composition pharmaceutique permet d'obtenir une absorption intestinale et une biodisponibilité biologique extrêmement élevées de l'ingrédient actif du point de vue pharmaceutique, en particulier lorsque l'ingrédient actif du point de vue pharmaceutique est médiocrement soluble dans l'eau.

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