A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2171955
The invention relates to pharmaceutical compositions for use as immunomodulator, comprising a purified preparation of a monoclonal antibody directed against the human interferon class I receptor (IFN-R) characterized by the following properties: it recognizes the extracellular domain of the human IFN-R, and it has a neutralizing capacity against the biological properties of the human type I-IFN. It further concerns their use for the diagnosis.
L'invention se rapporte à des compositions pharmaceutiques utilisées en tant qu'immunomodulateurs, comprenant une préparation purifiée d'un anticorps monoclonal dirigé contre le récepteur d'interféron humain de la classe I (IFN-R), et caractérisées par les propriétés suivantes: reconnaissance du domaine extracellulaire de l'INF-R humain, et capacité de neutralisation dressée contre les propriétés biologiques de l'I-IFN de type humain. On a également prévu leur utilisation diagnostique.
Benizri Eric Jacob
Tovey Michael G.
Benizri Eric Jacob
Fetherstonhaugh & Co.
Laboratoire Europeen de Biotechnologie S.a.
Tovey Michael G.
LandOfFree
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