Pharmaceutical composition comprising no or at least a no...

A - Human Necessities – 61 – K

Patent

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Details

IPC codes

A61K 33/00 (2006.01) A61K 31/04 (2006.01) A61K 31/198 (2006.01) A61K 31/26 (2006.01) A61K 31/5377 (2006.01) A61K 33/24 (2006.01)

Type

Patent

Patent number

CA 2376302

Description

The invention concerns the use of NO, a NO donor compound or a compound capable or releasing, stimulating or inducing NO formation in cells to prepare a medicine for treating or preventing a disease resulting from deficiency of an adult gene in a person for the re-expression of said homologous foetal gene. The invention particularly concerns the treatment of Duchenne or Becker muscular dystrophy, or thalassemia or sickle cell disease.

La présente invention concerne l'utilisation de NO, d'un composé donneur de NO ou d'un composé capable de libérer, de favoriser ou d'induire la formation de NO dans les cellules pour la préparation d'un médicament destiné au traitement ou à la prévention d'une maladie résultant de la déficience d'un gène adulte chez un individu par la ré-expression dudit gène foetale homologue. La présente invention concerne tout particulièrement le traitement des dystrophies musculaires, comme la dystrophie musculaire de Duchenne ou de Becker, ou la thalassémie ou la drépanocytose.

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