A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4965 (2006.01) A61K 31/215 (2006.01) A61P 31/16 (2006.01) A61P 43/00 (2006.01) C07D 241/24 (2006.01)
Patent
CA 2677905
Disclosed is a pharmaceutical composition comprising a pyrazine derivative represented by the general formula: [wherein R1 and R2 independently represent a hydrogen atom or a halogen atom; and R3 represents a hydrogen atom or an amino-protecting group] or a salt thereof and at least one neuraminidase inhibitor. The pharmaceutical composition is useful for a treatment including the treatment or prevention of influenza. Also disclosed is a method of using these components in combination. The method is useful for a treatment including the treatment or prevention of influenza.
L'invention concerne une composition pharmaceutique comportant un dérivé de pyrazine représenté par la formule générale : [dans laquelle R1 et R2 représentent indépendamment un atome d'hydrogène et un atome d'halogène ; et R3 représente un atome d'hydrogène ou un groupe protecteur amino] ou un sel de celui-ci ou au moins un inhibiteur de neuraminidase. La composition pharmaceutique s'utilise pour un traitement comprenant le traitement ou la prévention de la grippe. L'invention concerne également un procédé d'utilisation de ces composants en combinaison. Le procédé s'utilise pour un traitement comportant le traitement ou la prévention de la grippe.
Marks & Clerk
Toyama Chemical Co. Ltd.
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