Pharmaceutical composition containing a drug and sirna

Details Pharmaceutical composition containing a drug and sirna Pharmaceutical composition containing a drug and sirna

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 31/713 (2006.01)

Patent

CA 2756499

The present invention relates generally to the fields of molecular biology, medicine, oncology, and delivery of ther-apeutic compounds. In particular, the present invention relates to pharmaceutical compositions containing a hydrophobic drug substance and an inhibitory nucleic acid molecule, such as short interfering RNA (siRNA), in a single drug delivery system, as well as a process for making and a process for administering the same.

La présente invention concerne d'une manière générale les domaines de la biologie moléculaire, de la médecine, de l'oncologie, et de l'administration de composés thérapeutiques. En particulier, la présente invention concerne des compositions pharmaceutiques contenant une substance de médicament hydrophobe et une molécule d'acide nucléique inhibiteur, tel qu'un petit ARN interférent (siARN), dans un système d'administration de médicament unique. L'invention porte en outre sur une méthode de réalisation et sur une méthode d'administration de ces compositions.

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