A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/616 (2006.01) A61K 9/16 (2006.01) A61K 9/24 (2006.01) A61K 9/50 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2324283
A pharmaceutical composition is provided which is useful for cholesterol lowering and reducing the risk of a myocardial infarction, which includes a statin, such as pravastatin, lovastatin, simvastatin, atorvastatin, cerivastatin or fluvastatin, in combination with aspirin, in a manner to minimize interaction of aspirin with the statin and minimize side effects of aspirin. A method for lowering cholesterol and reducing risk of a myocardial infarction employing such composition is also provided.
La présente invention concerne une composition pharmaceutique, utile pour l'abaissement du taux de cholestérol et la réduction du risque d'infarctus du myocarde. Cette composition comprend une statine, telle que la pravastatine, la lovastatine, la simvastatine, l'atorvastatine, la cérivastatine ou la fluvastatine, associée à l'aspirine d'une manière qui permet de minimiser l'interaction entre l'aspirine et la statine, ainsi que les effets secondaires de l'aspirine. La présente invention concerne aussi un procédé de réduction du cholestérol et du risque d'infarctus du myocarde par l'emploi d'une telle composition.
Jain Nemichand B.
Ullah Ismat
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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