C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 9/00 (2006.01) A61K 9/70 (2006.01) A61K 31/137 (2006.01) A61K 31/166 (2006.01) A61K 31/167 (2006.01) A61K 31/20 (2006.01) A61K 31/245 (2006.01) A61K 31/277 (2006.01) A61K 31/40 (2006.01) A61K 31/401 (2006.01) A61K 31/403 (2006.01) A61K 31/4045 (2006.01) A61K 31/4196 (2006.01) A61K 31/422 (2006.01) A61K 31/4422 (2006.01) A61K 31/445 (2006.01) A61K 31/4468 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61K 31/455 (2006.01) A61K 31/485 (2006.01) A61K 31/495 (2006.01) A61K 31/575 (2006.01) A61K 31/
Patent
CA 2259418
A pharmaceutical composition contains an acid addition salt of a basic drug and a fatty acid or bile acid. The acid addition salts thus formed exhibit enhanced transmucosal and transdermal penetration of the basic drug. The acid addition salts, an inclusion complex containing said salts and a use of said salts are also disclosed.
Une composition pharmaceutique contient un sel d'addition acide d'un médicament de base et un acide gras ou acide biliaire. Les sels d'addition acides ainsi formés ont des qualités améliorées de pénétration transmuqueuse et transdermique du médicament de base. L'invention concerne des sels d'addition acides, un complexe d'inclusion contenant lesdits sels et une forme d'utilisation desdits sels.
de Kock Lueta-Ann
Penkler Lawrence John
Whittaker Darryl Vanstone
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Farmarc Nederland B.v.
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