A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 9/48 (2006.01)
Patent
CA 2588465
Pharmaceutical compositions suitable for oral administration in solid dosage forms are described. The compositions comprise an effective amount of a drug compound in the form of a salt, wherein the drug salt is characterized by conversion to a less soluble form of the drug compound under certain pH conditions, and an anti-nucleating agent.
L'invention concerne des compositions pharmaceutiques conçues pour être administrées par voie orale et se présentant dans des formes galéniques solides. Les compositions comprennent une quantité efficace d'un composé médicamenteux sous la forme d'un sel, le sel médicamenteux étant caractérisé en ce qu'il est converti en une forme moins soluble du composé médicamenteux dans certaines conditions de pH et un agent d'anti-nucléation.
Artino Laura M.
Cruanes Maria T.
Xu Wei
Zhu Honggang
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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