C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 253/075 (2006.01) A61K 9/14 (2006.01) A61K 31/53 (2006.01)
Patent
CA 2483103
The present invention provides a pharmaceutical composition comprising a plurality of lamotrigine particles having a specific surface area of from about two to about three and a half meters per gram. Pharmaceutical compositions falling within the surface area criteria for the lamotrigine particles include those having a particle diameter equal to or less than about 100 ~m, preferably about 50 ~m, and most preferably 10 ~m. The pharmaceutical composition can be formulated into a wide variety of dosage forms.
La présente invention concerne une composition pharmaceutique contenant une pluralité de particules de lamotrigine ayant une aire spécifique d'environ 2 à environ 3 mètres et demi par gramme. Les compositions pharmaceutiques satisfaisant ces critères d'aire pour les particules de lamotrigine comprennent celles présentant un diamètre de particule égal ou inférieur à environ 100 ?m, de préférence environ 50 ?m, et idéalement 10 ?m. La composition pharmaceutique peut être formulée en une grande variété de formes galéniques.
Aronhime Judith
Samburski Guy
Heenan Blaikie Llp
Teva Pharmaceutical Industries Ltd.
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