Pharmaceutical composition containing sibutramine and orlistat

A - Human Necessities – 61 – K

Patent

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A61K 31/365 (2006.01) A61K 31/135 (2006.01)

Patent

CA 2315259

A method for the treatment of obesity in a human in need of such treatment which comprises administration to the human of therapeutically effective amount of a compound of formula (I) including enantiomers and pharmaceutically acceptable salts thereof, in which R1 and R2 are independently H or methyl, and a therapeutically effective amount of a compound of formula (II) wherein the compound of formula (I) and the compound of formula (II) are administered simultaneously, separately or sequentially.

L'invention concerne une méthode qui permet de traiter l'obésité chez un être humain ayant besoin dudit traitement. Celui-ci consiste à administrer audit être humain une quantité thérapeutiquement efficace d'un composé de formule (I), dans laquelle R¿1? et R¿2? sont indépendamment H ou méthyle, ou de ses énantiomères ou de ses sels pharmaceutiquement acceptables; et une quantité thérapeutiquement efficace d'un composé de formule (II). Le composé de formule (I) et le composé de formule (II) sont administrés simultanément, séparément ou successivement.

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