Pharmaceutical composition containing substance inhibiting...

Details Pharmaceutical composition containing substance inhibiting... Pharmaceutical composition containing substance inhibiting...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 31/192 (2006.01) A61K 31/353 (2006.01) A61K 31/355 (2006.01) A61K 38/16 (2006.01)

Patent

CA 2175985

A pharmaceutical composition comprising a substance inhibiting HSP47 production, selected from the group consisting of a malt extract, a flavonoid compound, a protein-bound-polysaccharide obtained from a fungus belonging to Coriolus versicolor, a paeoniflorin derivative, a tocopherol derivative, and a ferulic acid derivative, and a pharmaceutically acceptable carrier is disclosed. The substance inhibiting HSP47 production can efficiently improve physiological conditions of a patient suffering from diseases exhibiting pathosis of overproduction of the extracellular matrix, and efficiently treat such diseases. Further, the substance is useful for preventing or treating various diseases accompanied with abnormal growth of the vascularization.

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