A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 31/19 (2006.01) A61K 31/35 (2006.01) A61K 31/40 (2006.01) A61K 31/56 (2006.01) A61K 38/23 (2006.01) A61K 38/48 (2006.01) A61K 45/00 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61K 47/30 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2294457
The present invention provides a pharmaceutical composition for application to the mucosa to be used in drug therapy comprising a water-insoluble and/or water--low soluble substance, a medicament, and an aqueous medium, and having an osmotic pressure of less than 290 mOsm. This composition is superior over conventional pharmaceutical compositions for application to the mucosa, due to efficient and high permeability to the blood at the mucosa. The present invention further provides a pharmaceutical composition for application to the mucosa comprising a hemostatic agent and a medicament. This composition is superior over conventional pharmaceutical compositions for application to the mucosa, due to permeability and retentivity at the mucosa.
L'invention concerne des compositions médicinales à appliquer sur la muqueuse, à utiliser dans une pharmacothérapie, comprenant des substances insolubles dans l'eau et/ou difficilement solubles dans l'eau, des médicaments et des milieux aqueux, et développant une pression osmotique inférieure à 290 mOsm. Ces compositions sont supérieures aux compositions classiques de par leur aptitude à migrer de la muqueuse vers le sang. L'invention se rapporte encore à des compositions médicinales à appliquer sur la muqueuse, qui contiennent des médicaments et des compositions hémostatiques. Lesdites compositions sont supérieures aux compositions classiques de par leur osmose au niveau de la muqueuse et de leur rétentivité dans cette dernière.
Kawabe Hiroyuki
Kinoshita Wataru
Nishibe Yoshihisa
Borden Ladner Gervais Llp
Teijin Limited
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